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Pharmacological particulars
ATCvet code: QD06AA03
Antibiotics and chemotherapeutics for dermatological use.
Antibiotics for topical use.
Tetracycline and derivatives.
Pharmacodynamics
Oxytetracycline is produced by fermentation of Streptomyces rimosus.
It possesses broad spectrum antimicrobial activity against a wide range of gram +ve and gram -ve bacteria, certain mycoplasmas, protozoa, rickettsiae and Chlamydia.
Oxytetracycline is bacteriostatic and acts by inhibiting protein synthesis within the cell.
Pharmacokinetics
When administered topically, oxytetracycline absorption is negligible; it comes into direct contact with bacteria on the skin and in superficial lesions on external body surfaces. The marker dye indicates the extent of the treated area.