ATCvet code: QP 52 AA 01
Pharmacodynamics
The spectrum of action of praziquantel covers all the important species of cestodes in dogs. It specifically includes all Taenia species occurring in dogs, Multiceps multiceps, Joyeuxiella pasquali, Dipylidium caninum, Mesocestoides species, Echinococcus multilocularis and E. granulosus. Praziquantel is effective against all stages of development of these parasites occurring in the intestines of dogs.
Praziquantel impairs the normal tegument function of the parasite, making it permeable to excessive glucose loss and thereby more easily attacked by proteolytic enzymes. Because of this, whole tapeworms including the scolex are very rarely passed in the faeces following administration of the drug. Disintegrated and partially digested fragments may occasionally be seen in the faeces.
Pharmacokinetics
Praziquantel is rapidly absorbed by the animal and metabolised by the liver. It is excreted, entirely as metabolites, in the urine and faeces.
Shelf life
Shelf life of the veterinary medicinal product as packaged for sale: 3 years.
Shelf life after first opening the immediate packaging: use immediately.
Special precautions for storage
Do not store above 25 C.
Any unused half tablet should be discarded.
Special precautions for the disposal of unused veterinary medicinal product or waste materials derived from the use of such products
Medicines should not be disposed of via wastewater.
Use take-back schemes for the disposal of any unused veterinary medicinal product or waste materials derived thereof in accordance with local requirements and with any national collection systems applicable to the veterinary medicinal product concerned.